Open AccessHemostasis in Cold‐Knife Conization: Effects and side effects of glypressin R , a long‐acting analogue of lysine‐vasopressin
Author(s) -
Irestedt L.,
Thomassen P. A.,
Vilhardt H.
Publication year - 1986
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348609161488
Subject(s) - medicine , pallor , hemostasis , surgery , vasopressin , blood loss , randomized controlled trial
In a double‐blind, randomized study, 50 patients undergoing conization were treated with either lysine‐vasopressin (LVP) or its longer‐acting analogue Glypressin R . Bleeding during the operation and side effects were studied. The hemostatic effect appeared better with LVP than with Glypressin. One postoperative bleeding occurred in the whole series, in a patient treated with Glypressin. The effect on the general circulation, especially with respect to pallor of the skin, was less prominent with Glypressin than with LVP (with the concentrations used in this study).