Open AccessIncreased Arterial Catecholamines in Pre‐Eclampsia
Author(s) -
øian Pål,
Kjeldsen Sverre Erik,
Eide Ivar,
Maltau Jan Martin
Publication year - 1986
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348609158398
Subject(s) - medicine , blood pressure , epinephrine , eclampsia , dopamine , mean arterial pressure , norepinephrine , heart rate , venous blood , endocrinology , arterial blood , catecholamine , sympathetic nervous system , anesthesia , pregnancy , genetics , biology
Arterial and venous plasma catecholamines were measured in 13 pre‐eclamptic and 13 normotensive pregnant women. in the pre‐eclamptic group, arterial concentrations were higher for adrenalin (p<0.001), noradrenalin (p<0.05) and dopamine (p<0.01) than in the normotensive group, whereas in venous plasma only adrenalin (p<0.01) and dopamine levels were higher (p<0.05). Arterial adrenalin concentrations in the pre‐eclamptic group were, on average, three times as high as normotensive arterial adrenalin. the arterial‐venous (a‐v) differences were higher for adrenalin (p<0.001) and dopamine (p<0.05) in the preeclamptic than in the normotensive group. in the preeclamptic group, arterial adrenalin was correlated with mean arterial blood pressure (r=0.89, p<0.001) and with increased heart rate (r=0.78, p<0.01). According to these results, both sympathetic nervous and sympathetic adrenal activities are increased in patients with pre‐eclampsia.