Open AccessPlasma Concentrations of Motion, Somatostatin and Pancreatic Polypeptide Before, During and After Parturition
Author(s) -
Jenssen T. G.,
Hoist N.,
Burhol P. G.,
Jorde R.,
Maltau J. M.,
Vonen B.
Publication year - 1986
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348609158371
Subject(s) - medicine , somatostatin , endocrinology , pancreatic polypeptide , hormone , glucagon
The plasma concentrations of the gastrointestinal regulatory peptides motilin, somatostatin and pancreatic polypeptide were measured in 6 pregnant women, 17—35 years old. Plasma samples were drawn 2–3 weeks before, during, and immediately after labor, and 24 h as well as 1 year after delivery. Plasma motilin levels did not change during labor, but peaked non‐significantly upon delivery, and were thereafter significantly elevated 24 h post partum (p<0.05). Plasma motilin concentrations measured one year after delivery were almost identical with the pre‐term values. Plasma somatostatin rose non‐significantly during labor and peaked transiently upon delivery (p<0.05), whereas plasma pancreatic polypeptide increased significantly during the second stage of labor (p<0.05). the plasma motilin increase may be part of a compensatory mechanism leading to augmented gastrointestinal motility after delivery.