The Regulation of Menstrual Cycle and its Relationship to the Moon

A synchronous relationship between the menstrual cycle and lunar rhythm was confirmed by 1. Investigative data: Among the 826 female volunteers with a normal menstrual cycle, aged between 16 and 25 years, a large proportion of menstruations occurred around the new moon (28.3%), while at other times during the lunar month the proportion of menstruations occurring ranged between 8.5–12.6%; the difference was significant (p<0.01). 2. Laboratory findings: The 6‐hydroxymelatonin levels in the urina sanguinis of 3 female volunteers reached their zenith prior to and during menstruation, gradually declining to their nadir during ovulation. The difference in 6‐hydroxymelatonin between menstruation and ovulation was significant (p<0.01). Two of these three volunteers had their zenith in the period of the new moon and nadir 3—4 days prior to the full moon respectively. 3. Clinical experience: The lunar‐menses‐regulatory therapy in treatment of Nephropenic secondary amenorrhea revealed 4 clinical cure, 5 marked effect, 8 menogogue and 3 inef‐fect out of 20 cases.