
DOES ESTROGEN REPLACEMENT THERAPY PREDISPOSE TO THROMBOSIS?
Author(s) -
Åstedt Birger
Publication year - 1985
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348509157151
Subject(s) - medicine , thrombosis , estrogen , estrogen replacement therapy , climacteric , hormone replacement therapy (female to male) , gynecology , substitution therapy , estrogen therapy , intensive care medicine , menopause , testosterone (patch)
. Several studies have been carried out to evaluate the risk of thrombosis when using contraceptive steroids (for reference, see Åstedt 7). The estrogenic component of oral contraceptives (OC) has been held responsible for a thrombogenic effect (18, 22, 31). Similar extensive epidemiologic studies dealing with the risk of thrombosis when using climacteric substitution therapy are not available. However, the Boston Collaborative Drug Surveillance Program (38) was unable to show any relationship between estrogen replacement therapy and thrombosis.