Open AccessCONCENTRATION OF UNCONJUGATED ESTRIOL IN CAPILLARY WHOLE BLOOD FROM PREGNANT WOMEN
Author(s) -
Axelsson Ove,
Hofstedt Margareta,
Wide Leif
Publication year - 1985
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348509156371
Subject(s) - estriol , medicine , venous blood , whole blood , capillary action , endocrinology , hormone , materials science , composite material
. A radio‐immunological method applied to the estimation of unconjugated estriol in capillary whole blood is described. The concentration of unconjugated estriol in capillary whole blood and venous serum from 35 pregnant women was measured. Close relation was found between values in venous serum and capillary whole blood. The intra‐assay variation was 4.9% for venous and 7.8 % for capillary whole blood samples when analysed in duplicate. The day‐to‐day variability was of the same order for venous (10.0%) as for capillary (8.4%) samples. It is concluded that unconjugated estriol can be measured in small amounts (25 μl) of capillary whole blood and that this method offers practical advantages over methods using venous serum or plasma.