Open AccessTHYROID HORMONES IN THE HUMAN PREGNANCY
Author(s) -
Tolino A.,
Conciliis B.,
Montemagno U.
Publication year - 1985
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348509156362
Subject(s) - medicine , pregnancy , hormone , first trimester , second trimester , erythropoietin producing hepatocellular (eph) receptor , thyroid , endocrinology , thyroid hormones , fetus , obstetrics , receptor , genetics , biology , receptor tyrosine kinase
. Radio‐immunologic T 3 , T 4 , FT 3 , FT 4 , rT 3 , TBG and 17β‐estradiol were measured in women in the 2nd and 3rd trimester of pregnancy, during labor, and during the first 14 days of the puerperium. A group of women suffering with gestosis EPH were also investigated. Our data suggest that in women suffering with gestosis EPH and during labor in normal pregnancy there is a T 3 ‐selective defect (low T 3 syndrome) in which the conversion route of T 4 into T 3 is inhibited while the conversion route of T 4 into rT 3 remains fully operative, resulting in low plasma levels of T 3 and FT 3 and normal levels of T 4 , normal or high levels of FT 4 and high levels of reverse T 3 .