Open AccessTHE DISAPPEARANCE OF HUMAN CHORIONIC GONADOTROPIN FROM PLASMA AND URINE FOLLOWING INDUCED ABORTION
Author(s) -
Lugt B.,
Drogendijk A. C.
Publication year - 1985
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348509156360
Subject(s) - abortion , medicine , urine , human chorionic gonadotropin , pregnancy , gonadotropin , endocrinology , gynecology , andrology , obstetrics , hormone , biology , genetics
. In 28 females, daily measurement of the HCG concentration in urine and in 15 of them daily measurement of the β‐HCG concentration in plasma was carried out during the first 2 weeks following first‐trimester induced abortion by vacuum aspiration. Plasma β‐HCG concentration fell according to a multi‐exponential curve with a half‐life of 0.63 days in the first 2 days following induced abortion, and of 3.85 days in the subsequent 14 days. The disappearance of HCG from urine is exponential, with a half‐life value of 1.3 days. A urine pregnancy test with a sensitivity of 1 IU/ml wil nearly always be negative in the course of 2 weeks after abortion. A positive test 4 weeks after abortion indicates an incomplete abortion or persistent trophoblast.