GRANULOSA‐THECA CELL TUMOR IN A ONE‐YEAR‐OLD INFANT | Zendy

Lessing J. B. | Zendy; Michowitz M. | Zendy; Baratz M. | Zendy

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GRANULOSA‐THECA CELL TUMOR IN A ONE‐YEAR‐OLD INFANT

Author(s) -

Lessing J. B.,

Michowitz M.,

Baratz M.

Publication year - 1985

Publication title -

acta obstetricia et gynecologica scandinavica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.401

H-Index - 102

eISSN - 1600-0412

pISSN - 0001-6349

DOI - 10.3109/00016348509155145

Subject(s) - medicine , pubic hair , theca , breast development , endocrinology , physiology , gynecology , ovary , hormone

. A case is presented of a 12‐month‐old female infant, with sexual precocity due to a Granulosa‐Theca cell tumor which presented with vaginal bleeding, breast development and pubic hair growth. The 17β‐estradiol levels prior to operation were 300 pg/ml. Levels of gonadotropins were undetectable. Postoperative estradiol levels were measured and found to be 10 pg/ml. This tumor is very rare in infants, and there have been only four previously reported cases in children under 2 years of age.

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