Open AccessGRANULOSA‐THECA CELL TUMOR IN A ONE‐YEAR‐OLD INFANT
Author(s) -
Lessing J. B.,
Michowitz M.,
Baratz M.
Publication year - 1985
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348509155145
Subject(s) - medicine , pubic hair , theca , breast development , endocrinology , physiology , gynecology , ovary , hormone
. A case is presented of a 12‐month‐old female infant, with sexual precocity due to a Granulosa‐Theca cell tumor which presented with vaginal bleeding, breast development and pubic hair growth. The 17β‐estradiol levels prior to operation were 300 pg/ml. Levels of gonadotropins were undetectable. Postoperative estradiol levels were measured and found to be 10 pg/ml. This tumor is very rare in infants, and there have been only four previously reported cases in children under 2 years of age.