Open AccessINDUCTION OF LABOR
Author(s) -
Andreasson B.,
Bock Johannes E.,
Larsen J.
Publication year - 1985
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348509154710
Subject(s) - medicine , oxytocin , induction of labor , nasal administration , vaginal delivery , cervix , bishop score , significant difference , prostaglandin , obstetrics , gynecology , anesthesia , pregnancy , pharmacology , cancer , biology , genetics
Abstract. In a double‐blind randomized controlled study of 300 women, 150 primiparas and 150 multiparas, induction of labor by means of vaginal suppositories containing 3 mg prostaglandin E 2 (PGE 2 ) was compared with the conventional method of intranasal oxytocin and with a combined method of 3 mg PGE 2 vaginal suppositories alternating with intranasal oxytocin. In the PGE 2 group the intensity of delivery was significantly greater than in the oxytocin group, among both primiparas and multiparas and among the patients with ripe and unripe cervix. The efficiency of the combined treatment could no be evaluated because of the high intensity of delivery during the first 24 hours. There were no maternal side effects, and no significant difference in the frequencies of failed induction and cesarean section.