Open AccessDistribution of HLA‐antigens among patients with endometriosis
Author(s) -
Moen Mette,
Bratlie Anne,
Moen Torols
Publication year - 1984
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348409156977
Subject(s) - endometriosis , human leukocyte antigen , medicine , antigen , incidence (geometry) , immunology , disease , population , ethnic group , environmental health , physics , sociology , anthropology , optics
. Previous studies have demonstrated a hereditary tendency to develop endometriosis and the incidence of the disease varies in different ethnic groups. The genetic background to these differences has not been clearly explained. The present investigation was performed to seek a possible association between certain HLA antigens and endometriosis. One hundred patients were typed for HLA‐A, ‐B and ‐C, and of these 24 were also typed for HLA‐DR. No significant deviations from the antigen frequencies in a normal population were found. We conclude that the development of endometriosis does not seem to be associated with HLA‐A, ‐B, ‐C or ‐DR antigens.