Open AccessResults of in vitro fertilization and culture of human ova
Author(s) -
Lauritsen J. G.,
Therkelsen A. J.
Publication year - 1984
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348409156276
Subject(s) - embryo , andrology , human fertilization , in vitro fertilisation , oocyte , cleavage (geology) , in vitro , medicine , gynecology , anatomy , biology , microbiology and biotechnology , genetics , paleontology , fracture (geology)
. Using a technique with different media for fertilization and subsequent culture, cleavage of at least one oocyte was achieved in 35 (83%) out of 42 consecutive patients. A total of 138 oocytes (74 pre‐ovulatory, 20 non‐ovu‐latory and 44 atretic) were inseminated in vitro. Fifty‐two (70%) of the pre‐ovulatory oocytes clove and of these 37 (72%) developed apparently normally to the morula or blas‐tocyst stage, while cleavage of the remaining 15 (28%) was characterized by an abnormal growth curve or abnormal morphology of the embryo. Only one (5%) of the 20 non‐ovulatory oocytes clove, and this embryo displayed an abnormal growth curve. None of the atretic oocytes clove. It is concluded that evaluation of morphology and growth curve seems to be of value in distinguishing between apparently normally and abnormally developing embryos in vitro.