Open AccessAdenocarcinoma of the Endometrium Stage I
Author(s) -
Philipsen Torben,
Nørgård Mogens
Publication year - 1984
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348409156273
Subject(s) - medicine , stage (stratigraphy) , radium , hysterectomy , adenocarcinoma , surgery , survival rate , carcinoma , endometrium , urology , cancer , paleontology , physics , nuclear physics , biology
. Survival after treatment of stage 1 endometrial ad‐enocarcinoma was studied in a material of 111 patients, median follow‐up period 6 years. Routine treatment was preoperative intrauterine and vaginal radium followed, in 6 weeks, by total hysterectomy and bilateral salpingo‐oophorectomy. The 5‐year corrected survival after treatment by operation and/or irradiation was 93%, after irradiation alone 87%. A significantly better survival was found in stage la (95%) than in stage Ib (83%) and also in patients with grade 1 tumors (97%) than in those with grade 3 tumors (71%). 21% of the patients had a residual endometrial tumor after preoperative radium, and among them survival was signifi‐canctly lower than in patients without residual tumor. The recurrence rate was 11.7%. Vaginal metastases did not occur. Our routine treatment afforded satisfactory results in stage 1, grade 1 and 2. However, supplementary treatment must be recommended in the case of grade 3 tumors, of myometrial deep invasion, and of residual tumor following preoperative radium therapy.