Open AccessAbnormally Elevated Pregnancy Specific β 1 Glycoprotein (SP 1 β) with Very low Placental Lactogen (hPL) Concentrations in a Pregnancy with Satisfactory Outcome
Author(s) -
Pledger D. R.,
McEwan Helen P.
Publication year - 1984
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348409155557
Subject(s) - medicine , pregnancy , placental lactogen , gestation , human placental lactogen , estrogen , creatinine , endocrinology , respiratory distress , urinary system , placenta , obstetrics , fetus , biology , surgery , genetics
. Pregnancies with very low maternal serum concentrations of placental function monitors, yet resulting in a normal outcome, have been reported occasionally before (4, 6). We report here a case in which maternal serum placental lactogen (hPL) concentratïons were very low, urinary estrogen output assessed by estrogen/creatinine ratio was satisfactory, but maternal serum pregnancy specific β 1 glycoprotein (SP 1 β) concentrations were grossly elevated. Ultrasound findings suggested impairment of growth. The outcome of the pregnancy was satisfactory, although the baby, apparently of 38‐40 weeks' gestation, developed mild respiratory distress.