Open AccessHormonal and Cytopathological Changes in Vaginal and Cervical Smears from women undergoing chemotherapy for extragenital Malignant Diseases
Author(s) -
Schachter Alexander,
Kopmar Alexander,
Avram Erna,
Gorodeski Israel G.,
Segal Anita
Publication year - 1983
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348309156260
Subject(s) - medicine , chemotherapy , malignancy , gynecology , vaginal smear , cervix , cytology , pathology , cancer , estrous cycle
. The effects of various chemotherapeutic drugs on the squamous epithelium of the cervicovaginal tissues were investigated in a test group of 74 and a control group of 44 women with advanced extragenital malignancy. The cyto‐logical findings were as follows (A) cytohormonal changes reflecting estrogenic withdrawal in pre‐ and postmenopausal women (B) reversible cytopathol'ogical changes reflecting a cytotox‐ic reaction, and (C) absence of premalignant and malignant changes.