Open AccessEpicutaneous Application of A2358 Compresses Containing Ketocaine for Pain Relief in Labor
Author(s) -
Jouppila R.,
Nuoranne E.,
Tervilä L.,
Gustafsson B.
Publication year - 1983
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348309156230
Subject(s) - medicine , anesthesia , pain relief , double blind , multicenter study , clinical trial , labor pain , surgery , randomized controlled trial , pregnancy , alternative medicine , pathology , placebo , biology , genetics
. In the present multicenter trial 147 primigravidae were treated for low‐back pain during the first stage of labor. 72 parturients were treated with A2358 compresses containing ketocaine, which were applied to the sacral lower‐back region for one hour, 75 parturients were treated identically with compresses without the anesthetic drug. The pain relieving effect was almost the same in both treatment groups. The low‐back pain was alleviated in about half of the mothers at 0.5, 10 and 1.5 hours after the application of both A2358 or control compresses. Supplementary analgesics had to be administered in about 60% of the parturients in both groups. The results show that factors other than ketocaine are involved in pain relief after application of A2358 compresses.