Open Access133 Xenon Clearance from Amniotic Fluid in Baboons During Administration of Oxytocin, Prostaglandin F 2α and A β‐ Mimetic Agent
Author(s) -
EinerJensen N.,
Lauersen N. H.,
Wilson K. H.
Publication year - 1983
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348309155753
Subject(s) - oxytocin , medicine , amniotic fluid , uterine contraction , uterus , prostaglandin , endocrinology , anesthesia , pregnancy , fetus , biology , genetics
. Amniotic fluid clearance of 133 xenon was measured in pregnant baboons near term during a control period of spontaneous uterine activity and during induction of contractions with oxytocin or PGF 2α and inhibition of activity by a β‐adrenergic agent, berotec. There was no significant change in the clearance of 133 xenon from the amniotic fluid during moderate uterine activity induced by oxytocin or PGF 2α . The clearance rate decreased five‐fold during infusion of berotec, compared with the control infusion periods, simultaneous with a decrease in uterine activity. When the berotec infusion was discontinued, the clearance of 133 xenon immediately returned to the previous level, while the return of uterine activity was more gradual.