Open AccessNeoplasia in the Vagina Following Hysterectomy for Dysplasia or Carcinoma in Situ of the Uterine Cervix
Author(s) -
Rasmussen Jan,
Diernaes Elisabeth
Publication year - 1983
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348309154216
Subject(s) - carcinoma in situ , vagina , medicine , cervix , dysplasia , hysterectomy , carcinoma , gynecology , pathology , cancer , surgery
. With a view to establishing some of the factors responsible for an increased risk of neoplasia in the vagina following primary hysterectomy for dysplasia or carcinoma in situ of the cervix, 63 surgical specimens from patients with subsequent neoplasia in the vagina have been compared with specimens from 40 patients without subsequent neoplasia. We found the frequency of neoplasia in the vagina to be greater when dysplasia or carcinoma in situ could be demonstrated in the vaginal margin. Neither the degree of endo‐cervical glandular involvement, the number of mitoses, nor the inflammatory response of the connective tissue appeared to be significant in this respect. No significant connection was found between the severity of the preinvasive lesion of the cervix and the subsequent neoplasia in the vagina.