Open AccessHISTOLOGICAL APPEARANCES OF THE HUMAN PLACENTA OBSERVED BY ELECTRON MICROSCOPY AFTER HYPERTONIC SALINE ABORTION
Author(s) -
Stegeman J. H. J.,
Treffers P. E.
Publication year - 1980
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348009160083
Subject(s) - hypertonic saline , hysterotomy , medicine , placenta , tonicity , abortion , andrology , decidua , electron microscope , human placenta , syncytiotrophoblast , intervillous space , pregnancy , microscopy , saline , pathology , gestation , fetus , endocrinology , biology , physics , optics , genetics
. Placentae obtained after Hypertonic Saline Induced Abortion (HSIA) were compared with placentae delivered by hysterotomy between 16 and 20 weeks of pregnancy. When investigated by routine light microscopy the greater part of the placental tissue seemed to be normal, changes were confined to a thin subchorionic layer. Transmission and scanning electron microscopy revealed serious damage especially to the syncytium, not only in the subchorial zone but also in the transitional and in the decidual zone. In vitro experiments demonstrated that a very short exposure to hypertonic solution can produce impressive histological changes in placental tissue.