Open AccessWATER AND ION METABOLISM IN PLACENTA (III)
Author(s) -
Castaldo F.,
Cittadini A.,
Romor R.,
Paparella P.,
And A. Bompiani,
Terranova T.
Publication year - 1980
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348009160078
Subject(s) - potassium , calcium , sodium , placenta , oxygen , metabolism , incubation , respiration , biophysics , endogeny , biochemistry , endocrinology , medicine , zoology , chemistry , fetus , biology , anatomy , pregnancy , organic chemistry , genetics
. Rabbit placenta slices incubated at 38°C in oxygenated medium, in the presence of endogenous substrates + 5 mM glucose, after a period of preincubation of 120 min at 0–1°C, show a net accumulation of potassium and extrusion of water, sodium and calcium. The movement of potassium, sodium and calcium appears to be related to the rate of oxygen consumption of the slices and to be inversely proportional to the age of the tissue. The efficiency of cations movement is also dependent on the nature and composition of the incubation medium. In this respect the potassium concentration of the medium plays a major role. The movement of water, on the other hand, seems to be completely independent from both the rate of respiration and the age of the tissue. The results are discussed in terms of relation between placenta age and senescence, and efficiency of the mechanisms devoted to the cell regulation of water and ions content.