Open AccessChronic Granulocytic Leukemia in Pregnancy: A Case Report and Review of the Literature
Author(s) -
Shalev Oded,
Heyman Samuel,
Hod Giora,
Adato Rahel
Publication year - 1980
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348009155453
Subject(s) - medicine , pregnancy , busulfan , abortion , chronic granulocytic leukemia , fetus , leukemia , obstetrics , second trimester , first trimester , gynecology , surgery , immunology , chemotherapy , cyclophosphamide , genetics , biology
Chronic granulocytic leukemia (CGL) was diagnosed in the second trimester of pregnancy in a mother of four, who decided to terminate the pregnancy immediately. According to the literature this unusual combination is not a definite indication for abortion since CGL does not adversely affect the course of the pregnancy nor the pregnancy alter the course of the disease. Prudent treatment with busulfan or splenic irradiation, when indicated, apparently does not endanger the development of the fetus.