Open AccessMonozygotic Twins with Dissimilar Phenotypes and Chromosome Complements
Author(s) -
Pedersen I. Krogh,
Philip J.,
Sele V.,
Starup J.
Publication year - 1980
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348009155429
Subject(s) - phenotype , medicine , genetics , chromosome , monozygotic twin , gene , biology
A case history of monozygotic twins is presented. Twin A showed gonadal dysgenesis and chromosomal mosaicism (45, X0/46, XX). Twin B was a phenotypical normal female with the karyotype 46, XX. Fifteen previous reports of monozygotic twins with gonadal dysgenesis are reviewed. Dissimilar phenotypes seem to be the rule rather than the exception, and mosaicism is found in the majority of cases with dissimilar phenotype. The assumption is made that the chromosome disorder leading to gonadal dysgenesis arises postzygotically, either before or after the process leading to twinning.