Open AccessControlled Sodium Bicarbonate Infusion and Maternal Acid‐Base Balance During Labor
Author(s) -
RonEl Raphael,
Caspi Eliahu,
Modai David
Publication year - 1980
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348009155400
Subject(s) - medicine , sodium bicarbonate , acid–base homeostasis , bicarbonate , cervical dilatation , anesthesia , sodium , group b , surgery , cervix , chemistry , organic chemistry , cancer
The effects of a controlled sodium bicarbonate (S.B.) infusion on the acid‐base balance of primiparas in normal labor and delivery were studied and compared to a similar control group of primiparas without S.B. infusion. Beginning at 6 cm cervical dilatation, 2mEq of S.B./kg of total body weight were infused to patients in the study until full cervical dilatation. The dosage given to this group emerged from a study of base deficit dynamics and space distribution of S.B. in a control group of patients during labor and delivery. Significant variations in pH, base excess, and plasma bicarbonate were observed, beginning 44±19 minutes after the S.B. infusion. These variations in acid‐base parameters persisted for 10 minutes following delivery. While no adverse effects were observed in our patients, this experimental design represents a preliminary approach toward correcting deleterious fetal acid‐base variations during labor and delivery.