Open AccessSerum Lactic Acid Dehydrogenase and Isoenzymes During Pregnancy and Labor
Author(s) -
Makkonen Maija,
Penttilä Ilkka M.,
Castrén Olli
Publication year - 1980
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348009154622
Subject(s) - medicine , lactic dehydrogenase , isozyme , lactic acid , pregnancy , l lactate dehydrogenase , obstetrics , gynecology , lactate dehydrogenase , enzyme , biochemistry , bacteria , biology , genetics
Total serum lactic acid dehydrogenase activity (LDH) and the levels of LDH isoenzymes were investigated in 14 women during early pregnancy (8–16th week), in 28 women during late pregnancy (29–37th week), in 73 at term (38–42nd week) and in 27 during labor (38–42nd week). LDH activity was found to be elevated in severe pre‐eclampsia and in chronic hypertensive women during pregnancy, as well as during normal and dysfunctional labor. No change was established in total serum LDH during normal pregnancy. LDH 1 was increased during late pregnancy and at term. In severe pre‐eclampsia and during normal labor it was decreased. LDH 2 was also decreased in severe pre‐eclampsia and during dysfunctional labor. LDH 3 was decreased during late pregnancy but increased in severe pre‐eclampsia. No change was observed in LDH 4 during pregnancy, or in labor. LDH 5 was increased in normal and dysfunctional labor.