Open AccessARTERIOGRAPHY AND CHEMOTHERAPY IN LOCALIZED TROPHOBLASTIC DISEASE, BY MEANS OF LOCAL‐ (PELVIC‐) INTRAARTERIAL INFUSION
Author(s) -
Goldman Jack A.,
Peleg Dan,
Agmon Moshe,
Shapiro Gerald
Publication year - 1979
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347909154609
Subject(s) - medicine , chemotherapy , uterus , disease , radiology , surgery
. In spite of considerable progress in systemic chemotherapy in malignant throphoblastic disease, there remains a small group of patients who fail to respond to this type of therapy. Here the trophoblastic process may be localized by means of an arteriography, and treated by a local, intraarterial infusion of cytotoxic compounds in high concentration. The latter makes possible the treatment of processes localized in essential organs which are hard to remove, as well as in young women wishing to preserve their reproductive capacity. Our experience is limited to one case of a young woman with chorioadenoma destruens in the uterus, resistant to systemic chemotherapy, yet sucessfully treated with pelvic, intraarterial infusion of cytotoxics.