Open AccessTREATMENT OF HYPERPROLACTINEMIC LUTEAL INSUFFICIENCY WITH BROMOCRIPTINE
Author(s) -
Andersen A. N.,
Larsen J. F.,
Eskildsen P. C.,
Knoth M.,
Micic S.,
Svenstrup B.,
Nielsen J.
Publication year - 1979
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347909154600
Subject(s) - bromocriptine , luteal phase , medicine , prolactin , infertility , endocrinology , galactorrhea , pregnancy , hormone , biology , genetics
. Twelve patients with infertility and insufficient luteal function were studied during a control cycle, and during a cycle when 2.5 mg of bromocriptine was given twice daily. Serum levels of prolactin, progesterone, estradiol‐17‐β, FSH and LH were determined during both cycles. Endometrial biopsies were taken from most patients during the late luteal phase. Two patients had persistent hyperprolactinemia, approximately 35‐45 ng/ml, and both had repeated insufficient luteal function, which completely reverted to normal during treatment. Five of the 10 normoprolactinemic patients achieved a normal luteal function during bromocriptine therapy. No pregnancies were achieved during the study but one patient later conceived during bromocriptine therapy.