Open AccessINTRAMUSCULAR ACTH OR PLACEBO IN THE TREATMENT OF HYPEREMESIS GRAVIDARUM
Author(s) -
Ylikorkala Olavi,
Kauppila Antti,
Ollanketo MaijaLiisa
Publication year - 1979
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347909154066
Subject(s) - hyperemesis gravidarum , medicine , placebo , pregnancy , vomiting , adrenocorticotropic hormone , intramuscular injection , anesthesia , hormone , alternative medicine , pathology , biology , genetics
. Thirty‐two women with hyperemesis gravidarum were treated with intramuscular ACTH (0.5 mg) or placebo for 4 days in a randomized double‐blind trial. The two treatments were equally effective in relieving hyperemesis, although the function of the adrenal cortex was stimulated only during the ACTH therapy. The administration of ACTH thus appears useless for the treatment of severe vomiting in early pregnancy.