Open AccessExtremely low placental lactogen hormone (hpl) values in an otherwise uneventful pregnancy preceding delivery of a normal baby
Author(s) -
Gaede Preben,
Trolle Dyre,
Pedersen Henning
Publication year - 1978
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347809154883
Subject(s) - medicine , human placental lactogen , placental lactogen , pregnancy , obstetrics , hormone , gynecology , placenta , endocrinology , fetus , biology , genetics
. A case of a normal pregnancy and delivery with extremely low placental lactogen hormone (hPL) values in maternal blood is presented. The low hPL‐values were due to the fact that the placenta only produced about 1/25 of the normal estimated output, calculated on the basis of the hPL‐concentration in the invervillous spaces. The concentrations of progesterone, the placenta‐specific β 1 ‐glycoprotein (SP 1 ) and total estriol in serum were normal, while prolactin and chorionic gonadotropin (hCG) were considerably elevated. Glucose levels were normal. At the ultrastructural level the actual placenta under study did not differ from a normal term placenta. In spite of the very low concentrations of hPL there was a good milk secretion, and the mother was still breast‐feeding her baby 11 months after the delivery. Basal level of prolactin was at this time normal.