Open AccessCryosurgical treatment of dysplasia and carcinoma in situ of the cervix uteri
Author(s) -
Einerth Yngve
Publication year - 1978
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347809154031
Subject(s) - medicine , carcinoma in situ , cervix , dysplasia , gynecology , carcinoma , obstetrics , cancer , pathology
. Fifty‐nine patients (age range 18–40 years, mean 28 years) with dysplasia or carcinoma in situ of the cervix uteri were treated with cryosurgery. Healing occurred in 54 patients (91.6%) after one treatment (“double‐freeze” technic) and in 2 patients after refreezing. No early or late complications occurred during a follow‐up period of 7–37 months. Five of the patients with carcinoma in situ were followed immunologically with determinations of serum TPA (tissue polypeptide antigen), which can be employed as a parameter of malignancy. In all instances, the initially elevated TPA normalized after cryosurgical treatment. Cryosurgery is a simple, painless and safe treatment method in ectocervically localized carcinoma in situ and dysplasia that is particularly suited for out‐patient use.