Open AccessSerum Human Placental Lactogen (HPL) Levels in Patients with Intact Hydatidiform Mole
Author(s) -
Lim Y. C.,
Chew S. C.,
Ratnam S. S.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609158523
Subject(s) - human placental lactogen , mole , radioimmunoassay , placental lactogen , medicine , gestation , human chorionic gonadotropin , endocrinology , gonadotropin , pregnancy , placenta , biology , hormone , fetus , genetics
. Serum human placental lactogen (HPL) levels in forty cases of intact hydatidiform mole were measured by radioimmunoassay. the HPL values were generally lower than normal pregnancies of the corresponding period of gestation. However, normal and occasionally higher than normal values were observed in a few cases. Serum HPL level alone is of some clinical use in the diagnosis of hydatidiform mole. When combined with human chorionic gonadotropin (HCG), a low HPL/HCG ratio for the corresponding period of amenorrhoea is a useful index in the diagnosis of hydatidiform mole.