Open AccessHistamine Metabolism and Female Sex Hormones in Women
Author(s) -
Jonassen F.,
Wetterqvist H.,
Granerus G.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609158521
Subject(s) - histamine , estrogen , endocrinology , medicine , hormone , excretion , endogeny , metabolism , physiology , urine
. Oral combined contraceptives did not seem to alter histamine metabolism in females. During treatment with gonadotrophic hormones in four amenorrhoeic patients there was a tendency towards increasing excretion of methylhistamine (MeHi) followed by a sudden decrease corresponding to changes in the urinary estrogen. the excretion of methylimidazoleacetic acid (MeImAA) seemed to parallel that of MeHi. the findings support the hypothesis that an endogenous surge of estrogen may influence histamine turnover in women. Women of postmenopausal age have about the same histamine metabolism as younger menstruating women. Estrogen medication relieved symptoms of hot flushes or sweats but did not seem to affect the histamine turnover.