Open AccessOutcome of Pregnancy After Clomiphene Therapy
Author(s) -
Ahlgren Mats,
Källen Bengt,
Rannevik Gunnar
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609158516
Subject(s) - medicine , incidence (geometry) , pregnancy , ovulation , obstetrics , childbirth , gynecology , gonadotropin , drug , endocrinology , hormone , genetics , physics , optics , biology , psychiatry
. Of 159 pregnancies conceived after clomiphene therapy, 141 ended in childbirth, including seven sets of twins. There was a probable increase in the number of infants born with major malformations. These were exclusively to women who had not previously borne a normal infant. The incidence of malformed infants compares well with that published after gonadotropin therapy. The possibly higher incidence of malformations seen after drug‐induced ovulation would therefore seem to be due to the underlying subfertility state and thus not a direct drug effect.