Open AccessPrevention of Intraperitoneal Adhesions by Dextran, Hydrocortisone and Chymotrypsin: An Experimental Study
Author(s) -
Järvinen P. A.,
Nummi S.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609156926
Subject(s) - chymotrypsin , dextran , hydrocortisone , medicine , dextran 70 , adhesion , endocrinology , surgery , biochemistry , enzyme , chemistry , trypsin , organic chemistry
. The purpose of an experimental study in guineapigs was to prevent adhesion formation in the intraabdominal space by simultaneous intraperitoneal infusion of hydrocortisone, dextran and chymotrypsin. An examination made three weeks after the operation revealed a highly significant ( p >0.001) difference in favour of the dextran, dextran‐chymotrypsin and dextran‐chymotrypsin‐hydrocortisone groups when compared with the NaCl and control groups.