Open AccessPhospholipid Concentrations in Amniotic Fluid from Diabetic Pregnant Women
Author(s) -
Skjæraasen J.,
Lindback T.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609156918
Subject(s) - amniotic fluid , phospholipid , medicine , gestation , respiratory distress , gestational age , obstetrics , pregnancy , pulmonary surfactant , endocrinology , fetus , andrology , anesthesia , biochemistry , biology , genetics , membrane
. Amniotic fluid phospholipid concentrations measured in 104 samples from 65 diabetic patients have been related to gestational age, the state of diabetes according to White's classification, and the development of the respiratory distress syndrome (RDS). There is statistically significant evidence of accelerated surfactant production in White classes D, F, from 34 to 37 weeks gestation. Classes A, B, C, have phospholipid concentrations not significantly different from a reference series. RDS occurred in 26% and was frequently associated with mature phospholipid concentrations. There was a significant correlation between low Apgar scores and subsequent development of RDS.