Open AccessThe Effect of a Copper Iud and Various “Inert” Iuds on the Histological Picture of the Rabbit Endometrium During Early Pseudopregnancy and Pregnancy
Author(s) -
Grundsell Hans,
Håkansson Leif,
Hägerstrand Inga
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609156805
Subject(s) - endometrium , medicine , uterus , pregnancy , genitourinary system , gynecology , copper , research methodology , health services , rabbit (cipher) , obstetrics , population , biology , chemistry , genetics , statistics , mathematics , environmental health , organic chemistry
. The influence of a copper IUD and two “inert” IUDs on the histological picture of the rabbit endometrium during early pseudopregnancy and early pregnancy was studied. The copper IUD markedly inhibited the endometrial maturation during the first five days of both pseudopregnancy and pregnancy. The “inert” IUDs had no such effect. The copper IUD prevented the normal response of the rabbit uterus to 17‐beta‐estradiol in castrated animals. The observed effects of the copper IUD might seriously interfere with the normal process of implantation.