
FOUR YEARS OVERALL EXPERIENCE WITH A NEW LOW ESTROGEN‐LOW PROGESTOGEN ORAL CONTRACEPTIVE
Author(s) -
Brat Th.
Publication year - 1976
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347609156451
Subject(s) - medicine , breakthrough bleeding , progestogen , norgestrel , family planning , metrorrhagia , incidence (geometry) , gynecology , obstetrics , pregnancy , clinical research , menstruation , estrogen , population , research methodology , physics , environmental health , biology , optics , genetics
. The reliability and the overall clinical acceptance of a new combined oral contraceptive, containing 30 mcg of ethinyl estradiol and 0.15 mg of D‐norgestrel, was studied in 102 patients over 1,731 cycles. The results have been accumulated over a period of four years, some of the subjects still using the presented formulation. No pregnancy occurred during the observation period. Out of the totally observed cycles, 94.3 per cent had a duration of 28 ± 2 days. In only 1.7 per cent of the cycles did withdrawal bleeding fail to appear. Spotting and breakthrough bleeding occurred in 3.6 and 3.8 per cent of the cycles respectively. The incidence of side‐effects reported by the users and commonly associated with oral contraceptive use was relatively low.