Open AccessGenetic Counselling in Myopathies of Childhood
Author(s) -
Tygstrup I.,
Plum P.
Publication year - 1974
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347409157194
Subject(s) - medicine , genetic counseling , muscular dystrophy , polymyositis , pediatrics , myopathy , eugenics , abortion , myositis , mitochondrial myopathy , physical therapy , pathology , pregnancy , mitochondrial dna , genetics , political science , law , biology , biochemistry , chemistry , gene
. The case history of two patients with myopathy, histologically diagnosed as myositis is reported. in both cases the physical signs, the course and later recognized familial cases gave the diagnosis progressive muscular dystrophy. in one case abortion was undertaken on medical, not on eugenic indication, and in the other a genetic counselling, based on the histologic diagnosis, led to the birth of a child who later developed clinical dystrophy. the histological criteria of polymyositis are discussed, and it is concluded that the histologic evaluation must be included in the overall diagnostic considerations, but should not be ascribed final importance.