Open AccessA STUDY OF COMPARATIVE EFFICACY OF ORAL PROSTAGLANDIN E 2 AS LIQUID FORMULATION AND TABLETS FOR INDUCTION OF LABOUR
Author(s) -
Obel Erik B.,
Larsen Jørgen Falck
Publication year - 1974
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347409156410
Subject(s) - medicine , alimentary tract , significant difference , prostaglandin , prostaglandin e , anesthesia
. 16 patients were treated with prostaglandin E 2 tablets and 15 patients with the liquid formulation. Seven of the patients who received tablets delivered vaginally within 24 houres (44 %). In the group treated with the liquid formulation eight patients delivered within 24 hours (53 %). Only three patients had severe side effects from the alimentary tract, but in all cases the treatment could be continued. No serious side effects were observed. As no significant difference between the tablets and liquid formulations was found, with regard to tolerance and efficacy, the tablets are recommended because they need no special preparation before use.