Open Access“Triggering” of Ovulation after Infusion of Synthetic Luteinizing Hormone Releasing Factor (LRF)
Author(s) -
Nakano Ryosuke,
Mizuno Tadayoshi,
Kotsuji Fumikazu,
Katayama Kazuaki,
Washio Motoo,
Tojo Shimpei
Publication year - 1973
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347309158325
Subject(s) - ovulation , medicine , luteinizing hormone , follicular phase , artificial insemination , gonadotropin releasing hormone , insemination , endocrinology , hormone , andrology , pregnancy , biology , sperm , genetics
. Synthetic luteinizing hormone releasing factor (LRF) was infused intravenously for 6 hours into two women who had donor insemination. Supplemental LRF was injected subcutaneously after a 6 hours continuous infusion. Ovulation was triggered by LRF infusion and two successful pregnancies were achieved. It is suggested that ovulation might be triggered by a continuous intravenous infusion of synthetic LRF, if follicular development of the ovary is sufficient. It is concluded that “triggering” of ovulation by a continuous infusion of LRF might be a convenient means for controlling the timing of ovulation in case of donor insemination.