Open AccessLong‐Term Use of Depot Medroxy Progesterone Acetate as a Contraceptive
Author(s) -
ElMahgoub S.,
Karim M.,
Ammar R.
Publication year - 1972
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347209156855
Subject(s) - medicine , medroxyprogesterone acetate , progestogen , family planning , depot , gynecology , fertility , thyroid function , metrorrhagia , menstruation , thyroid , hormone , research methodology , endocrinology , population , environmental health , archaeology , history
Depot Medroxy Progesterone Acetate 150 mg every 3 months was given to 231 women followed through 4 671 woman/months. The same progestogen in 300 mg dosage was given as six‐monthly injections to 92 women followed through 904 woman/months. These two dosage schedules were 100% effective in fertility control, the crude drop out rate reached 33.7% and 51.0% respectively. The menstrual cycles were markedly disorganized. The re‐establishment of normal menstrual and endometrial cycles and fertility after stopping therapy was reported. The effects on the genital organs, glucose tolerance, thyroid and liver function tests were studied.