Open AccessProgesterone Levels in Amniotic Fluid and Plasma from Women: II. Levels during Pregnancies Complicated by Rh‐Immunization or Hepatosis Gravidarum
Author(s) -
Jonasson L.E.,
Johansson E. D. B.
Publication year - 1971
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347109157336
Subject(s) - amniotic fluid , medicine , obstetrics , pregnancy , fetus , immunization , gynecology , antibody , immunology , biology , genetics
Using a protein binding technique, levels of progesterone were determined in 195 samples of amniotic fluid collected from 114 women. Most of the pregnancies were complicated by Rh‐immunization and parallel estimations of progesterone were performed in plasma or serum. The results show small variations between the various clinical groups. There was a significant rise in amniotic fluid progesterone concentration in pregnancies with very severe fetal erythroblastosis. Patients with hepatosis gravidarum showed a tendency towards high values both in amniotic fluid and in plasma. Progesterone determinations in amniotic fluid would be of limited practical value in the management of pregnancies complicated by Rh‐immunization.