Open AccessClear Cell Adenocarcinoma of the Female Genital Tract
Author(s) -
Hormia Martti,
Saloheimo Atso M.
Publication year - 1970
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016347009157248
Subject(s) - histogenesis , mesonephric duct , medicine , adenocarcinoma , vagina , clear cell adenocarcinoma , pathology , genitourinary system , clear cell , duct (anatomy) , incidence (geometry) , sex organ , gynecology , anatomy , carcinoma , biology , cancer , kidney , immunohistochemistry , physics , genetics , optics
. The incidence of clear cell type adenocarcinoma in the different parts of the genital canal, the age distribution of the patients, the clinical and histological picture and the theories advanced in the literature as to its histogenesis are reviewed. Four cases diagnosed in 1953–1968 at the Central Hospital of North Carelia are described. One of the tumours occurred in the vagina, two in the cervical canal and one in the ovary. The histopathological diagnosis may be difficult if a pronounced secondary infection is associated with the tumour tissue and the tumour cells are well differentiated. Clear cell adenocarcinoma and Schiller's mesonephroma are obviously two different histological manifestations of the same tumour, and they may also occur combined in the same tumour. That the site of origin is in the remnants of the mesonephric duct must be regarded as still unproved.