Open AccessConcentration of Malignant Cells from Vaginal Washings by Means of a New Type of Centrifuge
Author(s) -
Rastgeldi S.,
Turanli I.
Publication year - 1958
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016345809160053
Subject(s) - cervix , centrifuge , medicine , malignant cells , pathology , mucus , fractionation , detritus , isolation (microbiology) , uterus , cervical mucus , vagina , chromatography , cancer , microbiology and biotechnology , anatomy , biology , chemistry , ecology , physics , nuclear physics
A new type of centrifuge has been applied to the isolation and concentration of malignant cells obtained from cases of untreated invasive carcinoma of the cervix and uterus. It has been proved that the malignant cells do not lose their cytological identity during centrifugal fractionation of the solid elements obtained by vaginal washings. Diagnostically important cells have been satisfactorily separated from erythrocytes, mucus, detritus, and bacteria, and concentrated together with some other cells having the same specific gravity and/or size. Microscopic slides prepared by the technique described have facilitated identification of the malignant cells.