Open AccessPremalignant epithelial disorders of the vulva: squamous vulvar intraepithelial neoplasia, vulvar Paget's disease and melanoma in situ
Author(s) -
TERLOU ANNELINDE,
BLOK LEEN J.,
HELMERHORST THEO J.M.,
VAN BEURDEN MARC
Publication year - 2010
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016341003739575
Subject(s) - medicine , vulvar intraepithelial neoplasia , vulva , lichen sclerosus , vulvar diseases , dermatology , vulvar carcinoma , carcinoma in situ , intraepithelial neoplasia , vulvar neoplasm , vulvar cancer , extramammary paget's disease , disease , pathology , carcinoma , cancer , prostate
No standard screening programs exist to detect vulvar carcinoma or its precursor lesions, and therefore gynecologists, dermatologists and other healthcare providers in this field should be aware of the clinical features, behavior and management of the different existing premalignant vulvar lesions, squamous vulvar intraepithelial neoplasia (VIN), vulvar Paget's disease and melanoma in situ. In 2004, a new classification for squamous VIN was introduced by the International Society for the Study of Vulvar Disease, subdividing squamous VIN into the HPV‐related usual type , and into differentiated type , which is associated with lichen sclerosus. This review describes the relevant aspects of squamous VIN, vulvar Paget's disease and melanoma in situ, its epidemiological characteristics, diagnosis, management and malignant potential.