Open AccessPaget's disease of the vulva: evaluation of recurrence relative to symptom duration, volumetric excision of lesion, and surgical margin status
Author(s) -
ROH HYUNJIN,
KIM DAEYEON,
KIM JONGHYEOK,
KIM YONGMAN,
KIM YOUNGTAK,
NAM JOOHYUN
Publication year - 2010
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016341003674905
Subject(s) - medicine , vulva , surgical excision , lesion , surgery , margin (machine learning) , duration (music) , art , literature , machine learning , computer science
We analyzed recurrences with regard to symptom duration, volumetric excision, and surgical margin in 11 women with Paget's disease of the vulva. Data concerning demographics, surgical margin, and current state were collected. In addition, the three‐dimensional excisional skin and lesion size was determined from surgical and pathology reports. Recurrence was observed in 6 women where the symptom duration was longer than in those without recurrence (33 vs. 11 months, p < 0.02). During the initial operation, the fraction of removed normal skin was 85.3% in all the women, and 79.8% (range 67–97%) in those with recurrence and 92.0% (range 86–96%) in those without ( p < 0.04). Of 11 women, 8 had positive margins of whom 4 developed recurrence and 4 did not. Of the 3 patients with negative margins, 2 experienced recurrence but the third did not ( p = 0.58). Recurrence was not associated with positive margins, but correlated with symptom duration and volumetric excision.