Open AccessBiological risk factor of occupational morbidity with tuberculosis among medical professionals
Author(s) -
Пасечник Оксана Александровна,
Плотникова Ольга Владимировна,
Стасенко Владимир Леонидович,
Дымова Майя Александровна
Publication year - 2018
Publication title -
medicina truda i promyšlennaâ èkologiâ
Language(s) - English
Resource type - Journals
eISSN - 2618-8945
pISSN - 1026-9428
DOI - 10.31089/1026-9428-2018-8-52-57
Subject(s) - tuberculosis , medicine , risk factor , cluster (spacecraft) , immunology , environmental health , pathology , computer science , programming language
The article presents molecular genetic characteristics of M. tuberculosis circulating in Omsk region, as a biologic risk factor of tuberculosis morbidity among medical institutions workers. The authors used descriptive method of epidemiologic study, method of MIRUVNTR-typing of M. tuberculosis DNA. Findings are M. tuberculosis stains of Beijing genotype with VNTR-profile 233325173533424, isolated out of tuberculosis patients cluster being under stationary treatment. 65.2% of the stains had multiple drug-resistance to anti-tuberculosis medications. Respiratory tuberculosis was diagnosed in 85.4% of the cases, extra-pulmonary tuberculosis (urinary system, peripheral lymph nodes, eyes, CNS tuberculosis) equaled 14.6%. Nearly 30% of tuberculosis cases in the health care workers were associated with the bacterioexcretion.