CONDITION AND PROSPECTS INITIATED BY PROFESSOR V. YU. NEDAVA RESEARCH IN NANOBIOTECHNOLOGY

Doctor of Agricultural Sciences, Professor Volodymyr Yukhymovich Nedava (1925–2009) made a significant contribution to the development of selection, genetics and biotechnology in animal husbandry in Ukraine. His efforts laid the foundation for biotechnological foundations of farm animal reproduction and modern breed theory, substantiated the use of heterosis in livestock, effective methods of improving the brown Carpathian breed, simplified the method of assessing breeding animals for feed production. Goal. To analyze the directions of scientific activity of Doctor of Agricultural Sciences, Professor V. Yu. Nedava in the context of development of research in nanobiotechnology and to generalize its main achievements in developing the theory and methodology of application of ultra fine silica in media for cryopreservation of sperm farm animals. Methods. General scientific (analytical-synthetic, logical, systemic), biographical and source methods. The source base of the research covers a wide range of materials, which are based on archival documents and primary sources, scientific works (publications), reports and memoirs of colleagues about the talented scientist. Results. At the initiative and direct participation of V. Yu. Nedava, a method was developed for the treatment of bull semen, which differed from the conventional one in that in order to stabilize the biological value, to the freshly obtained sperm before dilution is added UFS at the rate of 3–30 mg per 1 billion sperm. Later, Professor V. Yu. Nedava and co-authors published the results of research on the use of fine pyrogenic UFS (Aerosil) as a stabilizer of the biological value of bull sperm, which was confirmed by higher fertility rates of heifers after insemination with Aerosil sperms (5.8% higher compared to control). Continuation of the initiated research of V. Yu. Nedava on the use of ultra fine silica to stabilize the cell surface of reproductive gametes was research on improving the technology of in vitro embryo formation and cryopreservation of male epididymal sperm using nanomaterials, which began in 2007. Conclusions. A number of scientific works of Professor Volodymyr Yukhymovich Nedava testify to his talented organizational and scientific character traits, which have a continuation in our time. V. Yu. Nedava initiated the development of the concept of VDK processing of semen of farm animals, determined their purpose in the system of conservation of genetic resources of farm animals, substantiated the importance of using such materials as the main link in the conservation of farm animals.