Open AccessSEROTONIN ACCELERATED PHARYNGEAL REGENERATION IN PLANARIAN SCHMIDTEA MEDITERRANEA TAIL FRAGMENTS
Author(s) -
Kreshchenko,
Grebenshchikova,
Karpov,
Mitkovsky
Publication year - 2020
Publication title -
theory and practice of parasitic disease control
Language(s) - English
DOI - 10.31016/978-5-9902341-5-4.2020.21.151-156
Subject(s) - planarian , planaria , turbellaria , biology , regeneration (biology) , flatworm , serotonin , pharynx , zoology , anatomy , microbiology and biotechnology , genetics , receptor
Serotonin has been identified in all classes of parasitic and free-living Platyhelminthes. Its function in the body of Platyhelminthes remains poorly studied. In present work, the serotonin effect on morphogenetic processes in planarian Schmidtea mediterranea was studied for the first time. Pharyngeal regeneration was studied in Schmidtea mediterranea planaria. Pharynx is a relatively autonomous organ with well differentiated morphological structure and specialized function. The dissected planarian body fragments were able to regenerate the new pharynx and restore its function – food uptake and feeding. It was observed that in group of animals, the pharynx regeneration occurred from day 5 to day 10 after amputation. The regeneration time varied in different experimental series and seems to depend on the season of the experiment. The maximum number of animals restored their feeding response for 6–8 days after the intervention. Under the serotonin treatments (10–0.001 µМ), the acceleration of the restoration of a new pharynx function has been observed as compared to the control animals. The preliminary results exhibit the stimulatory action of serotonin on pharyngeal regeneration in tail fragments of S. mediterranea, thus, indicating the morphogenetic properties of serotonin.