Study principles of problems of inborn defects in the context of the history of its development.

This article dwells upon the main periods of development of medicine geographic research of innate vices on the territory of the Union of Soviet Socialist Republics (USSR) and independent Ukraine. Many works of foreign scientists, which concern this problem have been analyzed in this article. Methodological principles of proliferation of birth defects, including analysis of methodological significance of A. Avtsyna of geographical pathology. The methods of research dissemination of birth defects, in this context, particular attention is paid to systematic approaches and whose role in the medical-geographical nature is essential. Key words: methodological principles, methods, birth defects, geographic pathology, medical geography.