Open AccessExtracorporeal hemocorrection in treatment of meningococcal septic shock in children
Author(s) -
K.V. Serednyakov,
К. В. Середняков,
Yuri Lobzin,
Ю. В. Лобзин
Publication year - 2019
Publication title -
rossijskij vestnik detskoj hirurgii, anesteziologii i reanimatologii
Language(s) - English
Resource type - Journals
eISSN - 2587-6554
pISSN - 2219-4061
DOI - 10.30946/2219-4061-2019-9-2-35-40
Subject(s) - medicine , extracorporeal , septic shock , refractory (planetary science) , hemofiltration , ards , intensive care medicine , renal replacement therapy , polymyxin b , surgery , hemodialysis , antibiotics , sepsis , lung , microbiology and biotechnology , biology , physics , astrobiology
Purpose: to estimate the effectiveness of extracorporeal hemocorrection in treatment of refractory meningococcal septic shock in children. Methods: patients with generalized form of meningococcal infection, multi-organ system failure and refractory septic shock admitted to the resuscitation department of Children’s Clinical Research Center for Infectious Diseases of the Federal Medical and Biological Agency of Russia underwent extracorporeal hemocorrection (polymyxin adsorption, continuous veno-venous hemofiltration, continuous veno-venous hemodiafiltration). MultiFiltrate apparatus was used (Fresenius Medical Care, Germany). Results: application of extracorporeal hemocorrection technique in the therapy of refractory meningococcal septic shock reduced the mortality from 44.4% to 25%. Conclusion: effectiveness of extracorporeal hemocorrection when treating patients with refractory meningococcal septic shock is established. A small number of examined patients is a limitation of the study.